Figure 1: Retention times with and without SCAT system.
Figure 2: Difference in density of methanol, performed by SGS.
Figure 3: Volume% difference, performed by SGS.
A vacuum can cause the pump to not receive enough fluid, resulting in irregular or interrupted fluid flow. This directly affects the reproducibility and accuracy of the measurements, visible in Figure 1.
A vacuum can cause the pump to not receive enough fluid, resulting in irregular or interrupted fluid flow. This directly affects the reproducibility and accuracy of the measurements, visible in Figure 1.
HPLC pumps are designed to deliver a constant flow of fluid. If a vacuum is created in the storage bottles, the pumps have to work harder, which can cause wear or damage.
A vacuum can cause air bubbles to form in the fluid system. These air bubbles can cause malfunctions, such as pressure fluctuations and erroneous signals from the detector.
Under vacuum conditions, unwanted substances can be drawn in through small openings or leaks, affecting the purity of the solvent.
The use of bottles with vent filters. Leaving the bottles open can cause several problems such as contamination, inhalation of harmful CMR substances, and liquids evaporating causing the eluent to no longer be in its original ratio, which can in turn affect retention times. In short; to improve accuracy, reproducibility, and the health of analysts, the right vent filters are needed.
By using the air valves from SCAT, all these problems are prevented. Satiata Laboratory Solutions supplies and installs these air vent filters for the HPLC.
For more information, please contact us.
HPLC Supply